Could widespread use of antiviral treatment curb the COVID-19 pandemic? A modeling study.

ABSTRACT:

Background

Despite the development of safe and effective vaccines, effective treatments for COVID-19 disease are still urgently needed. Several antiviral drugs have shown to be effective in reducing progression of COVID-19 disease.

Methods

In the present work, we use an agent-based mathematical model to assess the potential population impact of the use of antiviral treatments in four countries with different demographic structure and current levels of vaccination coverage: Kenya, Mexico, United States (US) and Belgium. We analyzed antiviral effects on reducing hospitalization and death, and potential antiviral effects on reducing transmission. For each country, we varied daily treatment initiation rate (DTIR) and antiviral effect in reducing transmission (AVT).

Results

SUBMITTER: Matrajt L 

PROVIDER: S-EPMC9361252 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature