Attractive targeted sugar bait phase III trials in Kenya, Mali, and Zambia.

ABSTRACT:

Background

Long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) target night-time indoor biting mosquitoes and effectively reduce malaria transmission in rural settings across Africa, but additional vector control tools are needed to interrupt transmission. Attractive targeted sugar baits (ATSBs) attract and kill mosquitoes, including those biting outdoors. Deployment of ATSBs incorporating the insecticide dinotefuran was associated with major reductions in mosquito density and longevity in Mali. The impact of this promising intervention on malaria transmission and morbidity now needs to be determined in a range of transmission settings.

Methods/design

We will conduct three similar stand-alone, open-label, two-arm, cluster-randomized, controlled trials (

SUBMITTER: Attractive Targeted Sugar Bait Phase III Trial Group 

PROVIDER: S-EPMC9361277 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature