The recombination landscape of the Khoe-San likely represents the upper limits of recombination divergence in humans.

ABSTRACT:

Background

Recombination maps are  important resources for epidemiological and evolutionary analyses; however, there are currently no recombination maps representing any African population outside of those with West African ancestry. We infer the demographic history for the Nama, an indigenous Khoe-San population of southern Africa, and derive a novel, population-specific recombination map from the whole genome sequencing of 54 Nama individuals. We hypothesise that there are no publicly available recombination maps representative of the Nama, considering the deep population divergence and subsequent isolation of the Khoe-San from other African groups.

Results

We show that the recombination landscape of the Nama does not cluster with any continental groups with publicly avail

SUBMITTER: van Eeden G 

PROVIDER: S-EPMC9361568 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature