Promoting independence in Lewy body dementia through exercise: the PRIDE study.

ABSTRACT:

Background

Lewy body dementia (LBD) is an aggressive type of dementia of rapid, fluctuating disease trajectory, higher incidence of adverse events, and poorer functional independence than observed in Alzheimer's disease dementia. Non-pharmacological treatments such as progressive, high-intensity exercise are effective in other neurological cohorts but have been scarcely evaluated in LBD.

Methods

The Promoting Independence in Lewy Body Dementia through Exercise (PRIDE) trial was a non-randomised, non-blinded, crossover pilot trial involving older adults with LBD consisting of a baseline assessment, an 8-week wait-list, and an 8-week exercise intervention. The aims of this study were to evaluate the determinants of the primary outcome functional independence, as measured by th

SUBMITTER: Inskip MJ 

PROVIDER: S-EPMC9361699 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature