Comparison of mainstream end tidal carbon dioxide on Y-piece side versus patient side of heat and moisture exchanger filters in critically ill adult patients: a prospective observational study.

ABSTRACT: The purpose of the study was to investigate the accuracy of mainstream EtCO₂ measurements on the Y-piece (filtered) side of the heat and moisture exchanger filter (HMEF) in adult critically ill patients, compared to that on the patient (unfiltered) side of HMEF. We conducted a prospective observational method comparison study between July 2019 and December 2019. Critically ill adult patients receiving mechanical ventilation with HMEF were included. We performed a noninferiority comparison of the accuracy of EtCO₂ measurements on the two sides of HMEF. The accuracy was measured by the absolute difference between PaCO₂ and EtCO₂. We set the non-inferiority margin at + 1 mmHg in accuracy difference between the two sides of HMEF. We also assessed the

SUBMITTER: Tamashiro S 

PROVIDER: S-EPMC9362078 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature