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An efficient 2-aminothiazolesalicylaldehyde fluorescent chemosensor for Fe²⁺ ion detection and a potential inhibitor of NUDT5 signaling hormone for breast cancer cell and molecular keypad lock application.

ABSTRACT: A novel thiazole phenol conjugate, 2-aminothiazolesalicylaldehyde (receptor1) was designed and synthesized for the first time through a single step process via Schiff base condensation reaction. The formation of receptor1 was confirmed by FTIR, ¹³C NMR, and ¹H NMR. The IR spectra confirmed the presence of the aldimine formation. It is further supported by the proton NMR, showing the disappearance of aldehyde peaks and the formation of a new imine peak. This is further corroborated by the ¹³C NMR. The receptor1 complexing with various metal ions were studied through fluorescence spectroscopy showed its selectivity toward Fe²⁺ ion following a reverse photoinduced electron transfer (PET) process compared to all other potentially competing ions. The

SUBMITTER: Basha SB

PROVIDER: S-EPMC9362492 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

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An efficient 2-aminothiazolesalicylaldehyde fluorescent chemosensor for Fe²⁺ ion detection and a potential inhibitor of NUDT5 signaling hormone for breast cancer cell and molecular keypad lock application.

OmicsDI is part of the ELIXIR infrastructure

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Dataset Information

An efficient 2-aminothiazolesalicylaldehyde fluorescent chemosensor for Fe2+ ion detection and a potential inhibitor of NUDT5 signaling hormone for breast cancer cell and molecular keypad lock application.

OmicsDI is part of the ELIXIR infrastructure

Tweets

An efficient 2-aminothiazolesalicylaldehyde fluorescent chemosensor for Fe²⁺ ion detection and a potential inhibitor of NUDT5 signaling hormone for breast cancer cell and molecular keypad lock application.