Incidence and prognosis associated with troponin elevation after cardiac surgery: a prospective cohort study

ABSTRACT:

Objective

Cardiac troponin is used as a prognostic biomarker after cardiac surgery. However, numerous confounding elements, such as inflammation, liver and renal function biomarkers, have been associated with troponin variations. Furthermore, several thresholds regarding the definition of myocardial infarction have been suggested. We aimed to confirm the accuracy of troponin, analysed as time-dependent variable, to predict mortality independently from other biomarkers; and to assess the incidence and prognosis of a 10 times upper normal value threshold (troponin10N) used in the current fourth definition of myocardial infarction.

Methods

In a prospective cohort of patients who underwent cardiopulmonary bypass cardiac procedures, we assessed the association between serum le

SUBMITTER: Clement A 

PROVIDER: S-EPMC9362836 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature