Clinical characteristics and depression score response after parathyroidectomy in primary hyperparathyroidism.

ABSTRACT:

Objective

Several studies indicate that patients with primary hyperparathyroidism (PHPT) undergoing parathyroid surgery have improvement in mood and neuropsychological functioning. The current analysis aims to examine the relationship between biochemical and clinical variables and the improvement in depression scores and in specific symptoms, after parathyroidectomy.

Design

A prospective observational case-control study at a referral centre.

Patients

Patients with PHPT undergoing parathyroidectomy (n = 88) or thyroid surgery (n = 85).

Measurements

The Patient Health Questionnaire-9 (PHQ-9) was utilized to obtain depression scores at enrolment and 12 months after surgery. The changes in PHQ-9 were analysed and correlated with baseline clinical and biochemical pa

SUBMITTER: Kearns AE 

PROVIDER: S-EPMC9362855 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature