Pseudo-T2 mapping for normalization of T2-weighted prostate MRI.

ABSTRACT:

Objective

Signal intensity normalization is necessary to reduce heterogeneity in T2-weighted (T2W) magnetic resonance imaging (MRI) for quantitative analysis of multicenter data. AutoRef is an automated dual-reference tissue normalization method that normalizes transversal prostate T2W MRI by creating a pseudo-T2 map. The aim of this study was to evaluate the accuracy of pseudo-T2s and multicenter standardization performance for AutoRef with three pairs of reference tissues: fat/muscle (AutoRef_F), femoral head/muscle (AutoRef_FH) and pelvic bone/muscle (AutoRef_PB).

Materials and methods

T2s measured by multi-echo spin echo (MESE) were compared to AutoRef pseudo-T2s in the whole prostate (WP) and zones (PZ and TZ/CZ/AFS) for seven asymptomatic

SUBMITTER: Sorland KI 

PROVIDER: S-EPMC9363383 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature