Short-term exposure to PM_2.5 components and renal health: Findings from the Veterans Affairs Normative Aging Study.

ABSTRACT: There is little evidence on the short-term impact of fine particulate matter (PM_2.5) on renal health, and the potential interactions and various influences of PM_2.5 components on renal health have not been examined. We investigated whether short-term (≤28 days) ambient PM_2.5 and 15 PM_2.5 components were associated with serum uric acid (SUA), blood urea nitrogen (BUN), estimated glomerular filtration rate (eGFR), and odds of incident chronic kidney disease (CKD) using both mixed-effect and Bayesian kernel machine regression (BKMR) models in the Normative Aging Study. This analysis included 2466 study visits from 808 older males enrolled during 1998-2016 with available data. BKMR showed positive relationships of PM_2.5 mixture with SUA an

SUBMITTER: Gao X 

PROVIDER: S-EPMC9363515 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature