Cognition impairment and risk of subclinical cardiovascular disease in older adults: The atherosclerosis risk in communities study.

ABSTRACT:

Background

Clinical cardiovascular disease (CVD) and cognition impairment are common and often coexist in aging populations, and CVD is associated with greater cognition impairment risk; however, the association between cognition impairment and CVD risk is inconsistent. It is unknown if pathways that contribute to CVD are caused by impaired cognition. We hypothesized that cognition impairment would be associated with greater subclinical CVD including subclinical myocardial damage [assessed by high-sensitivity cardiac troponin T (hs-cTnT)] and cardiac strain or dysfunction [assessed by N-terminal pro-B-type natriuretic peptide (NT-proBNP)].

Methods

This analysis included Atherosclerosis Risk in Communities Study (ARIC) participants who underwent global cognition z-scor

SUBMITTER: Li D 

PROVIDER: S-EPMC9363767 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature