Auditory brainstem development of naked mole-rats (Heterocephalus glaber).

ABSTRACT: Life underground often leads to animals having specialized auditory systems to accommodate the constraints of acoustic transmission in tunnels. Despite living underground, naked mole-rats use a highly vocal communication system, implying that they rely on central auditory processing. However, little is known about these animals' central auditory system, and whether it follows a similar developmental time course as other rodents. Naked mole-rats show slowed development in the hippocampus suggesting they have altered brain development compared to other rodents. Here, we measured morphological characteristics and voltage-gated potassium channel K_v3.3 expression and protein levels at different key developmental time points (postnatal days 9, 14, 21 and adulthood) to determine whethe

SUBMITTER: McCullagh EA 

PROVIDER: S-EPMC9363996 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature