A fatal neonatal case of fungemia due to Exophiala dermatitidis-case report and literature review.

ABSTRACT:

Background

Systemic infections caused by the black yeast-like fungus Exophiala dermatitidis are rare, but are associated with high mortality especially in immunocompromised patients. We report the first case of E. dermatitidis fungemia in a premature extremely low birth weight (ELBW) neonate who succumbed despite antifungal therapy with liposomal amphotericin (AMB) and fluconazole. A systematic review of all fungemia cases due to E. dermatitidis was also conducted aiming for a better understanding of the risk factors, treatment strategies and outcomes.

Case presentation

A male, ELBW premature neonate, soon after his birth, developed bradycardia, apnoea and ultimately necrotizing enterocolitis with intestinal perforation requiring surgical intervention. Meanwhile, he had also

SUBMITTER: Mpakosi A 

PROVIDER: S-EPMC9364490 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature