Tear proteomics analysis of patient suffered from delayed mustard gas keratopathy.

ABSTRACT: Understanding the molecular and cellular mechanisms involved in the pathogenesis of ocular injured induced by mustard gas can help better identify complications and discover appropriate therapies. This study aimed to analyze the proteomics of tears of chemical warfare victims with mustard gas ocular injuries and compare it with healthy individuals. In this case-control research, 10 mustard gas victims with long-term ocular difficulties (Chronic) were included in the patient group, while 10 healthy persons who were age and sex matched to the patients were included in the control group. Schirmer strips were used to collect the tears of the participants. Proteomics experiments were performed using the high-efficiency TMT10X method to evaluate the tear protein profile, and statistical bioinfor

SUBMITTER: Parvin S 

PROVIDER: S-EPMC9364592 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature