Association between dietary acid load and cancer risk and prognosis: An updated systematic review and meta-analysis of observational studies

ABSTRACT: Epidemiological studies have suggested that dietary acid load (DAL) might be related to the risk and prognosis of cancer, whereas the evidence is contentious. Several high-quality observational studies have been published following a prior systematic review with only one study included. Consequently, we conducted an updated systematic review and meta-analysis to comprehensively investigate the relationship between DAL and cancer risk and prognosis. A systematic literature search was conducted in the PubMed, Embase, and Web of Science databases from inception to 26 October 2021. Summary relative risks (RRs) with 95% CIs were calculated using a random-effects model. Publication bias, subgroup, meta-regression, and sensitivity analyses were also conducted. Ten observational studies (six cohor

SUBMITTER: Wang R 

PROVIDER: S-EPMC9365077 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature