SARS-CoV-2 antibody persistence after five and twelve months: A cohort study from South-Eastern Norway.

ABSTRACT:

Objectives

To assess total antibody levels against Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS CoV-2) spike protein up to 12 months after Coronavirus Disease (COVID-19) infection in non-vaccinated individuals and the possible predictors of antibody persistence.

Methods

This is the first part of a prospective multi-centre cohort study.

Participants

The study included SARS-CoV-2 real-time polymerase chain reaction (RT-PCR) positive and negative participants in South-Eastern Norway from February to December 2020. Possible predictors of SARS-CoV-2 total antibody persistence was assessed. The SARS-CoV-2 total antibody levels against spike protein were measured three to five months after PCR in 391 PCR-positive and 703 PCR-negative participants; 212 PCR-positive p

SUBMITTER: Sarjomaa M 

PROVIDER: S-EPMC9365168 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature