Change in Ocular Surface Staining during Eyelid Warming Is Related to Tear Cytokine Levels.

ABSTRACT:

Purpose

To investigate the changes in the tear cytokine profile of patients with meibomian gland dysfunction (MGD) treated with eyelid warming and to correlate these changes with clinical parameters for dry eye disease (DED).

Methods

Seventy patients with MGD were included and treated with the warming of eyelids. Of these, 61 still used the treatment three months after baseline, while 48 completed the whole treatment period of six months. The concentrations of 39 cytokines in the tear fluid were measured at baseline and after three and six months of treatment. All participants were examined with tests for DED, including tear film break-up time (TBUT), ocular surface staining (OSS), and the self-reporting Ocular Surface Disease Index (OSDI). Changes in cytokine concentrations

SUBMITTER: Landsend ECS 

PROVIDER: S-EPMC9365595 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature