Therapeutically dosed low molecular weight heparins in renal impairment: a nationwide survey.

ABSTRACT:

Purpose

International guidelines vary in their recommendations whether or not to reduce the therapeutic dose of low molecular weight heparins (LMWHs) in renal impairment. The use of anti-Xa monitoring as a basis of dose adjustments is also a matter of debate. As this may lead to variations in treatment policies, we aimed to study the treatment policies of therapeutically dosed LMWHs in renal impairment in Dutch hospitals.

Methods

An 11-item survey was distributed between June 2020 and March 2021 to hospital pharmacists, representing Dutch hospital organisations. Primary outcomes were the dosing regimens of therapeutically dosed LMWHs in renally impaired patients. Secondary outcomes were the proportion of hospitals that used anti-Xa monitoring and the anti-Xa target range use

SUBMITTER: Jaspers TCC 

PROVIDER: S-EPMC9365729 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature