Development of a model to predict psychotherapy response for depression among Veterans.

ABSTRACT:

Background

Fewer than half of patients with major depressive disorder (MDD) respond to psychotherapy. Pre-emptively informing patients of their likelihood of responding could be useful as part of a patient-centered treatment decision-support plan.

Methods

This prospective observational study examined a national sample of 807 patients beginning psychotherapy for MDD at the Veterans Health Administration. Patients completed a self-report survey at baseline and 3-months follow-up (data collected 2018-2020). We developed a machine learning (ML) model to predict psychotherapy response at 3 months using baseline survey, administrative, and geospatial variables in a 70% training sample. Model performance was then evaluated in the 30% test sample.

Results

32.0% of patients re

SUBMITTER: Ziobrowski HN 

PROVIDER: S-EPMC9365879 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature