Predicting the rupture status of small middle cerebral artery aneurysms using random forest modeling.

ABSTRACT:

Objective

Small intracranial aneurysms are increasingly being detected; however, a prediction model for their rupture is rare. Random forest modeling was used to predict the rupture status of small middle cerebral artery (MCA) aneurysms with morphological features.

Methods

From January 2009 to June 2020, we retrospectively reviewed patients with small MCA aneurysms (<7 mm). The aneurysms were randomly split into training (70%) and internal validation (30%) cohorts. Additional independent datasets were used for the external validation of 78 small MCA aneurysms from another four hospitals. Aneurysm morphology was determined using computed tomography angiography (CTA). Prediction models were developed using the random forest and multivariate logistic regression.

Results

SUBMITTER: Zhou J 

PROVIDER: S-EPMC9366079 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature