Measures of Utility Among Studies of Genomic Medicine for Critically Ill Infants: A Systematic Review.

ABSTRACT:

Importance

Genomic medicine holds promise to revolutionize care for critically ill infants by tailoring treatments for patients and providing additional prognostic information to families. However, measuring the utility of genomic medicine is not straightforward and has important clinical and ethical implications.

Objective

To review the ways that researchers measure or neglect to measure the utility of genomic medicine for critically ill infants.

Evidence review

This systematic review included prospective full-text studies of genomic medicine of both whole exome and genome sequencing in critically ill infants younger than 1 year. PubMed, Embase, Scopus, and Cochrane Library databases, the Cochrane Database of Systematic Reviews, and the ClinicalTrials.gov register we

SUBMITTER: Callahan KP 

PROVIDER: S-EPMC9366540 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature