Construction and validation of prognostic nomograms for elderly patients with metastatic non-small cell lung cancer.

ABSTRACT:

Background

Metastatic non-small cell lung cancer (NSCLC) is mostly seen in older patients and is associated with poor prognosis. There is no reliable method to predict the prognosis of elderly patients (≥60 years old) with metastatic NSCLC. The aim of our study was to develop and validate nomograms which accurately predict survival in this group of patients.

Methods

NSCLC patients diagnosed between 2010 and 2015 were all identified from the Surveillance, Epidemiology, and End Results (SEER) database. Nomograms were constructed by significant clinicopathological variables (p < 0.05) selected in multivariate Cox analysis regression.

Results

A total of 9584 patients met the inclusion criteria and were randomly allocated in the training (n = 6712) and validation (n = 2872

SUBMITTER: Sun H 

PROVIDER: S-EPMC9366578 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature