The space-time profiles of sleep spindles and their coordination with slow oscillations on the electrode manifold.

ABSTRACT: Sleep spindles are important for sleep quality and cognitive functions, with their coordination with slow oscillations (SOs) potentially organizing cross-region reactivation of memory traces. Here, we describe the organization of spindles on the electrode manifold and their relation to SOs. We analyzed the sleep night EEG of 34 subjects and detected spindles and SOs separately at each electrode. We compared spindle properties (frequency, duration, and amplitude) in slow wave sleep (SWS) and Stage 2 sleep (S2); and in spindles that coordinate with SOs or are uncoupled. We identified different topographical spindle types using clustering analysis that grouped together spindles co-detected across electrodes within a short delay (±300 ms). We then analyzed the properties of spindles of each ty

SUBMITTER: Malerba P 

PROVIDER: S-EPMC9366646 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature