Construction of a non-enzymatic electrochemical sensor based on graphitic carbon nitride nanosheets for sensitive detection of procalcitonin.

ABSTRACT: In this study, we established a label free and ultrasensitive electrochemical sensor based on graphitic nitride nanosheets (g-C₃N₄ NS) for procalcitonin (PCT) detection. Firstly, an easy-to-prepare and well-conducting g-C₃N₄ NS was synthesized. Next the g-C₃N₄ NS was immobilized on the electrode surface by π-π stacking, and further used to anchor the specific recognition peptide (PP). The surface morphology and structure after g-C₃N₄ NS and PP modification was characterized by X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM) and electrochemistry. The sensing property of this sensor was evaluated by differential pulse voltammetry (DPV) and showed a detection sensitivity with a dynami

SUBMITTER: Liu Y 

PROVIDER: S-EPMC9366762 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature