Metabolic alterations in alga Chlamydomonas reinhardtii exposed to nTiO₂ materials.

ABSTRACT: Nano-sized titanium dioxide (nTiO₂) is one of the most commonly used materials, however the knowledge about the molecular basis for metabolic and physiological changes in phytoplankton is yet to be explored. In the present study we use a combination of targeted metabolomics, transcriptomics and physiological response studies to decipher the metabolic perturbation in green alga Chlamydomonas reinhardtii exposed for 72 h to increasing concentrations (2, 20, 100 and 200 mg L^-1) of nTiO₂ with primary sizes of 5, 15 and 20 nm. Results show that the exposure to all three nTiO₂ materials induced perturbation of the metabolism of amino acids, nucleotides, fatty acids, tricarboxylic acids, antioxidants but not in the photosynthesis. The alterations

SUBMITTER: Liu W 

PROVIDER: S-EPMC9367718 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature