The Screening of Therapeutic Peptides for Anti-Inflammation through Phage Display Technology.

ABSTRACT: For the treatment of inflammatory illnesses such as rheumatoid arthritis and carditis, as well as cancer, several anti-inflammatory medications have been created over the years to lower the concentrations of inflammatory mediators in the body. Peptides are a class of medication with the advantages of weak immunogenicity and strong activity, and the phage display technique is an effective method for screening various therapeutic peptides, with a high affinity and selectivity, including anti-inflammation peptides. It enables the selection of high-affinity target-binding peptides from a complex pool of billions of peptides displayed on phages in a combinatorial library. In this review, we will discuss the regular process of using phage display technology to screen therapeutic peptides, and th

SUBMITTER: Zhang K 

PROVIDER: S-EPMC9368796 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature