Plasma Transfusion in Septic Shock-A Secondary Analysis of a Retrospective Single-Center Cohort.

ABSTRACT: In sepsis, both beneficial and detrimental effects of fresh frozen plasma (FFP) transfusion have been reported. The aim of this study was to analyze the indication for and effect of FFP transfusion in patients with septic shock. We performed a secondary analysis of a retrospective single-center cohort of all patients treated for septic shock at the interdisciplinary surgical intensive care unit (ICU) of the Heidelberg University Hospital. Septic shock was defined according to sepsis-3 criteria. To assess the effects of FFP administration in the early phase of septic shock, we compared patients with and without FFP transfusion during the first 48 h of septic shock. Patients who died during the first 48 h of septic shock were excluded from the analysis. Primary endpoints were 30- and 90-day

SUBMITTER: Dietrich M 

PROVIDER: S-EPMC9369152 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature