Adenoid Cystic Carcinoma of the Breast May Be Exempt from Adjuvant Chemotherapy.

ABSTRACT: Consistent standards regarding whether postoperative adjuvant chemotherapy is required in the treatment of adenoid cystic carcinoma of the breast (ACCB) are currently lacking. Using clinical data from the Surveillance, Epidemiology, and End Results (SEER) database (1988-2015), and the National Cancer Center of China (2004-2020), we retrospectively analyzed patients with ACCB who received radical treatment. A total of 661 patients were eligible. The median age at diagnosis was 61 years; 99.5% of patients were initially diagnosed with stage I and II breast cancer, and 76.7% had triple-negative breast cancer. Only 12.4% of patients received adjuvant chemotherapy. Multivariate analysis showed that patients with lymph node metastasis and non-radiotherapy had worse overall survival (OS) (p

SUBMITTER: Li L 

PROVIDER: S-EPMC9369505 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature