Uterus Transplantation: Revisiting the Question of Deceased Donors versus Living Donors for Organ Procurement.

ABSTRACT: Uterus transplantation is a surgical treatment for women with congenital or acquired uterine factor infertility. While uterus transplantation is a life-enhancing transplant that is commonly categorized as a vascular composite allograft (e.g., face or hand), it is similar to many solid organ transplants (e.g., kidney) in that both living donors (LDs) and deceased donors (DDs) can be utilized for organ procurement. While many endpoints appear to be similar for LD and DD transplants (including graft survival, time to menses, livebirth rates), there are key medical, technical, ethical, and logistical differences between these modalities. Primary considerations in favor of a LD model include thorough screening of donors, enhanced logistics, and greater donor availability. The primary considerat

SUBMITTER: Frisch EH 

PROVIDER: S-EPMC9369769 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature