Micronutrients and Renal Outcomes: A Prospective Cohort Study.

ABSTRACT:

Background

Micronutrients are essential in maintaining normal human physiology. Data regarding the association between micronutrients and renal outcomes in chronic kidney disease (CKD) are lacking.

Methods

This prospective observational cohort study enrolled 261 patients with CKD stages 1-5 and 30 subjects with normal renal function. Baseline serum zinc (Zn), selenium (Se), chromium, manganese, and copper, and laboratory tests were performed at enrolment. The primary endpoint was the presence of end-stage renal disease (ESRD) requiring long-term renal replacement therapy.

Results

The median follow-up periods of renal and non-renal survivals were 67.78 and 29.03 months, respectively. Multiple linear regression showed that Zn and Se (β ± SE: 24.298 ± 8.616, p = 0

SUBMITTER: Chen CY 

PROVIDER: S-EPMC9370256 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature