Synthesis of Halopyrazole Matrine Derivatives and Their Insecticidal and Fungicidal Activities.

ABSTRACT: Matrine is a traditional botanical pesticide with a broad-spectrum biological activity that is widely applied in agriculture. Halopyrazole groups are successfully introduced to the C13 of matrine to synthesize eight new derivatives with a yield of 78-87%. The insecticidal activity results show that the introduction of halopyrazole groups can significantly improve the insecticidal activity of matrine on Plutella xylostella, Mythimna separata and Spodoptera frugiperda with a corrected mortality rate of 100%, which is 25-65% higher than matrine. The fungicidal activity results indicate that derivatives have a high inhibitory effect on Ceratobasidium cornigerum, Cibberella sanbinetti, Gibberrlla zeae and Collectot tichum gloeosporioides. Therein

SUBMITTER: Cheng X 

PROVIDER: S-EPMC9370413 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature