Synthesis and Characterization of Dendronized Gold Nanoparticles Bearing Charged Peripheral Groups with Antimicrobial Potential.

ABSTRACT: Dendronized gold nanoparticles (AuNPs) were synthesized bearing charged peripheral groups. Two novel AB₃-type dendrons were synthesized with a thiol group at the focal point followed by their attachment to AuNPs. Dendrons were designed to have nine charged peripheral groups (carboxyl or amine), glycol solubilizing, units and one thiol moiety at the focal point. Both dendrons and all intermediates were synthesized in high yields and characterized by nuclear magnetic resonance spectroscopy (NMR) and mass spectrometry (MS). The amine- and carboxyl-terminated dendrons were used to functionalize gold nanoparticles (AuNPs) previously stabilized with citrate. The nanoparticles' diameters and their colloidal stability were investigated using dynamic light scattering (DLS). The size and

SUBMITTER: Perli G 

PROVIDER: S-EPMC9370457 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature