Cardiovascular disease risk in women living with HIV.

ABSTRACT:

Purpose of review

To synthesize current evidence on the impact of cardiovascular disease among women living with HIV (WLWH) with a particular focus on disease prevalence, mechanisms and prevention.

Recent findings

HIV-related cardiovascular disease risk is 1.5-fold to 2-fold higher for women than for men. Mechanisms of enhanced risk are multifactorial and include reinforcing pathways between traditional risk factors, metabolic dysregulation, early reproductive aging and chronic immune activation. These pathways influence both the presentation of overt syndromes of myocardial infarction, stroke and heart failure, as well as subclinical disease, such as microvascular dysfunction and cardiac fibrosis. Cardiovascular disease, therefore, remains a consistent threat to healthy agi

SUBMITTER: Kentoffio K 

PROVIDER: S-EPMC9370828 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature