Changes to the Gut Microbiome in Young Children Showing Early Behavioral Signs of Autism.

ABSTRACT: The human gut microbiome has increasingly been associated with autism spectrum disorder (ASD), which is a neurological developmental disorder, characterized by impairments to social interaction. The ability of the gut microbiota to signal across the gut-brain-microbiota axis with metabolites, including short-chain fatty acids, impacts brain health and has been identified to play a role in the gastrointestinal and developmental symptoms affecting autistic children. The fecal microbiome of older children with ASD has repeatedly shown particular shifts in the bacterial and fungal microbial community, which are significantly different from age-matched neurotypical controls, but it is still unclear whether these characteristic shifts are detectable before diagnosis. Early microbial colonization

SUBMITTER: Jones J 

PROVIDER: S-EPMC9371947 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature