Prognostic factors in completely resected lymph-node-negative pulmonary adenocarcinoma.

ABSTRACT:

Background

Lymph node involvement is one of the important prognostic factors for early-stage lung cancer. However, in lymph node-negative (N0) lung cancer the recurrent rate may be as high as 30%. We aimed to study potential prognostic factors including clinicopathological factors and epidermal growth factor receptor (EGFR) mutation status in this lung cancer population.

Methods

We retrospectively reviewed the medical records and pathological examinations of patients with completely resected N0 pulmonary adenocarcinoma treated in our institute between 2009 and 2016. We used Cobas^® test to determine EGFR mutation status. Recurrence-free survival (RFS) was analyzed by univariable and multivariable Cox regression analyses.

Results

We recruited 220 patients wit

SUBMITTER: Pakvisal N 

PROVIDER: S-EPMC9372192 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature