Reinfection rate of hepatitis C in HIV-1 positive men who have sex with men: A systematic review and meta-analysis.

ABSTRACT:

Purpose

A reduction of 80% in new Hepatitis C virus (HCV) infection is expected by 2030. However, high HCV reinfection rates have been reported among the high-risk population. This meta-analysis aimed to assess the HCV reinfection rate after successful treatment of HIV-1 coinfected MSM populations.

Methods

Bibliographic databases were searched and a random-effect model was utilized to calculate the pooled HCV reinfection rate. Sub-group and meta-regression were used to explore heterogeneity among selected studies. A funnel plot and Egger's regression test were performed to estimate the publication bias.

Results

Sixteen studies with 9,017.2 person-years (PY) follow-up were included. The overall HCV reinfection rate following successful treatment among HIV-1-infected MS

SUBMITTER: Wan Z 

PROVIDER: S-EPMC9372531 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature