Longitudinal changes of lactopontin (milk osteopontin) in term and preterm human milk.

ABSTRACT:

Background

Lactopontin (LPN) in breast milk, also known as milk osteopontin is thought to play a myriad of important roles in infants when they are immature. The purpose of the present study was to examine the longitudinal changes in LPN concentrations in term and preterm milk, and elucidate the links between maternal characteristics, LPN levels, and child growth in a birth cohort.

Methods

131 mothers who delivered term, moderate-late preterm (MPT), very preterm (VPT), and extremely preterm (EPT) infants were included, milk samples were collected at 7, 14, 28, and 120 days postpartum. LPN concentration was determined by multiple reaction monitoring (MRM) using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).

Results

Our results indicated

SUBMITTER: Zhu J 

PROVIDER: S-EPMC9372532 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature