Correlation of CT-derived pectoralis muscle status and COVID-19 induced lung injury in elderly patients.

ABSTRACT:

Objectives

To explore the association between CT-derived pectoralis muscle index (PMI) and COVID-19 induced lung injury.

Methods

We enrolled 116 elderly COVID-19 patients linked to the COVID-19 outbreak in Nanjing Lukou international airport. We extracted three sessions of their CT data, including one upon admission (T1), one during the first 2 weeks when lung injury peaked (T2) and one on day 14 ± 2 (T3). Lung injury was assessed by CT severity score (CTSS) and pulmonary opacity score (POS). Pneumonia evolution was evaluated by changes of CT scores at T2 from T1(Δ).

Results

The maximum CT scores in low PMI patients were higher than those of normal PMI patients, including CTSS1 (7, IQR 6-10 vs. 5, IQR 3-6, p < 0.001), CTSS2 (8, IQR 7-11 vs. 5, IQR 4-7, p < 0.001) and

SUBMITTER: Ying-Hao P 

PROVIDER: S-EPMC9372984 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature