[The effect of epinephrine for the treatment of spinal-hypotension: comparison with norepinephrine and phenylephrine, clinical trial].

ABSTRACT:

Background and objectives

Limited data are present on safety and efficiency of epinephrine for the prophylaxis and treatment of spinal-hypotension. This study was conducted to compare the effect of epinephrine with norepinephrine and phenylephrine on the treatment of spinal-hypotension and ephedrine requirement during cesarean delivery.

Methods

One hundred and sixty parturients with uncomplicated pregnancies undergoing elective cesarean delivery under spinal anesthesia were recruited. They were allocated randomly to receive norepinephrine 5 μg.mL^-1 (n=40), epinephrine 5 μg.mL^-1 (n=40), phenylephrine 100 μg.mL^-1 (n=40) or 0.9% saline infusions (n=40) immediately after induction of spinal anesthesia. Whenever systolic blood pressure drops to le

SUBMITTER: Biricik E 

PROVIDER: S-EPMC9373668 | biostudies-literature | 2020 Sep - Oct

REPOSITORIES: biostudies-literature