Multiple fluorescence response behaviours to proteins/bacteria and selective antibacterial activity of cetylpyridinium chloride (CPC)-based cationic carbon dots.

ABSTRACT: Direct interaction between carbon dots (CDs) and biomolecules leads to changes in the chemical and physical status as well as properties of CDs, which can have various biological and biomedical applications. In this work, the surface of CDs was modified with cetylpyridinium chloride (CPC) to facilitate interactions between CDs and biomolecules. Multiple fluorescence response behaviours of CPC-based CDs were observed towards several proteins (bovine serum albumin, lysozyme, protamine, and hemoglobin) and bacterial cells (Escherichia coli and Staphylococcus aureus). Electrostatic attraction and hydrogen bonding were involved in inducing aggregation of CDs and fluorence enhancement. An inner filter effect might also occur to reduce fluorescence of CDs when interacting with prote

SUBMITTER: Yang C 

PROVIDER: S-EPMC9373843 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature