Influence of genotype and perioral musculature on maxillary and mandibular development.

ABSTRACT:

Objectives

To determine whether there is an association between skeletal jaw position and perioral musculature, and if genotypes can predict skeletal growth.

Materials and methods

A prospective study on 42 patients over 1 year was performed. The study included 22 females and 20 males with and average age of 28.5 years. Lip strength was compared to radiographic cephalometric measurements. Allelic and genotypic frequencies from polymorphisms rs678397 and rs1815739 in ACTN3 and rs10850110 in MYO1H were compared to each variable. Chi-square and Fisher exact tests were used to determine if differences were statistically significant (alpha = 0.05).

Results

The data showed significant differences between rs678397 genotype and allele frequencies and SNA angle (P = .01; P = .0

SUBMITTER: Hansen SE 

PROVIDER: S-EPMC9374360 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature