Cancer-specific mortality in breast cancer patients with hypothyroidism: a UK population-based study.

ABSTRACT:

Purpose

Epidemiological studies have indicated a higher prevalence of hypothyroidism in breast cancer patients, possibly related to shared risk factors and breast cancer treatments. However, few studies have evaluated how hypothyroidism impacts survival outcomes in breast cancer patients. We aimed to determine the association between hypothyroidism and breast cancer-specific and all-cause mortality.

Methods

We conducted a population-based study using the Scottish Cancer Registry to identify women diagnosed with breast cancer between 2010 and 2017. A matched comparison cohort of breast cancer-free women was also identified. Using hospital diagnoses and dispensed prescriptions for levothyroxine, we identified hypothyroidism diagnosed before and after breast cancer diagnosis an

SUBMITTER: McVicker L 

PROVIDER: S-EPMC9374643 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature