Nine out of ten samples were mistakenly switched by The Orang-utan Genome Consortium.

ABSTRACT: The Sumatran orang-utan (Pongo abelii) reference genome was first published in 2011, in conjunction with ten re-sequenced genomes from unrelated wild-caught individuals. Together, these published data have been utilized in almost all great ape genomic studies, plus in much broader comparative genomic research. Here, we report that the original sequencing Consortium inadvertently switched nine of the ten samples and/or resulting re-sequenced genomes, erroneously attributing eight of these to the wrong source individuals. Among them is a genome from the recently identified Tapanuli (P. tapanuliensis) species: thus, this genome was sequenced and published a full six years prior to the species' description. Sex was wrongly assigned to five known individuals; the numbers in one sample identifie

SUBMITTER: Banes GL 

PROVIDER: S-EPMC9374732 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature