Longitudinal impact of trauma in the North American Prodrome Longitudinal Study-3.

ABSTRACT:

Aim

Individuals at clinical high risk (CHR) for psychosis have been shown to experience more trauma than the general population. However, although the effects of trauma appear to impact some symptoms it does not seem to increase the risk of transition to psychosis. The aim of this article was to examine the prevalence of trauma, and its association with longitudinal clinical and functional outcomes in a large sample of CHR individuals.

Methods

From the North American Prodrome Longitudinal Study-3 (NAPLS-3) 690 CHR individuals and 91 healthy controls from nine study sites between 2015 and 2018 were assessed. Historical trauma experiences were captured at baseline. Participants completed longitudinal assessments measuring clinical outcomes including positive and negative sympt

SUBMITTER: Farris MS 

PROVIDER: S-EPMC9374846 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature