A state-of-the-science review and guide for measuring environmental exposure biomarkers in dried blood spots.

ABSTRACT:

Background

Dried blood spot (DBS) sampling is a simple, cost-effective, and minimally invasive alternative to venipuncture for measuring exposure biomarkers in public health and epidemiological research. DBS sampling provides advantages in field-based studies conducted in low-resource settings and in studies involving infants and children. In addition, DBS samples are routinely collected from newborns after birth (i.e., newborn dried blood spots, NDBS), with many states in the United States permitting access to archived NDBS samples for research purposes.

Objectives

We review the state of the science for analyzing exposure biomarkers in DBS samples, both archived and newly collected, and provide guidance on sample collection, storage, and blood volume requirements associated

SUBMITTER: Jacobson TA 

PROVIDER: S-EPMC9375076 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature