Analysis of Rates of Brain Metastases and Association With Breast Cancer Subtypes in Ontario, Canada.

ABSTRACT:

Importance

Approximately 1 in 7 patients with metastatic breast cancer (MBC) will receive radiotherapy for brain metastases (BRM). Significant differences in cumulative incidence of BRM by breast cancer subtype may inform future BRM screening protocols.

Objective

To describe cumulative incidence of BRM among patients with de novo MBC.

Design, setting, and participants

In this population-based cohort study, population health administrative databases in Ontario, Canada, held at the ICES were used to identify patients diagnosed with de novo MBC between 2009 and 2018. Given that a code for BRM does not exist within ICES, we analyzed the incidence of radiotherapy for BRM. The median (IQR) follow-up was 19.3 (6.2-39.5) months. A total of 100 747 patients with a new diagnosi

SUBMITTER: Wang XY 

PROVIDER: S-EPMC9375172 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature