Thermal Degradants Identified from the Vaping of Vitamin E Acetate.

ABSTRACT: Studies have suggested that vitamin E acetate (VEA), when used in an electronic vaping device, undergoes thermal degradation and is considered one of the main contributors in e-cigarette or vaping product use-associated lung injury (EVALI). Using a Borgwaldt 5.1 linear smoker, a SVS250 Electronic Vaporizer and two types of tank systems, VEA was analyzed for degradation products produced via the Cooperation Centre for Scientific Research Relative to Tobacco method 81 when the filter containing vaporized VEA was extracted using acetonitrile. Two of the major products identified were 2,3,5,6-tetramethyl-1,4-benzoquinone and 2,6,10,14-tetramethyl-1-pentadecene, which were confirmed using analytical standards and gas chromatography-high-resolution mass spectrometry (GC-HRMS). Additional synthes

SUBMITTER: Kovach AL 

PROVIDER: S-EPMC9375236 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature