Performance comparison of Agilent new SureSelect All Exon v8 probes with v7 probes for exome sequencing.

ABSTRACT: Exome sequencing is becoming a routine in health care, because it increases the chance of pinpointing the genetic cause of an individual patient's condition and thus making an accurate diagnosis. It is important for facilities providing genetic services to keep track of changes in the technology of exome capture in order to maximize throughput while reducing cost per sample. In this study, we focused on comparing the newly released exome probe set Agilent SureSelect Human All Exon v8 and the previous probe set v7. In preparation for higher throughput of exome sequencing using the DNBSEQ-G400, we evaluated target design, coverage statistics, and variants across these two different exome capture products. Although the target size of the v8 design has not changed much compared to the v7 desig

SUBMITTER: Belova V 

PROVIDER: S-EPMC9375261 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature