A composite strategy of genome-wide association study and copy number variation analysis for carcass traits in a Duroc pig population.

ABSTRACT:

Background

Carcass traits are important in pig breeding programs for improving pork production. Understanding the genetic variants underlies complex phenotypes can help explain trait variation in pigs. In this study, we integrated a weighted single-step genome-wide association study (wssGWAS) and copy number variation (CNV) analyses to map genetic variations and genes associated with loin muscle area (LMA), loin muscle depth (LMD) and lean meat percentage (LMP) in Duroc pigs.

Results

Firstly, we performed a genome-wide analysis for CNV detection using GeneSeek Porcine SNP50 Bead chip data of 3770 pigs. A total of 11,100 CNVs were detected, which were aggregated by overlapping 695 CNV regions (CNVRs). Next, we investigated CNVs of pigs from the same population by whole-genome

SUBMITTER: Ding R 

PROVIDER: S-EPMC9375371 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature