Cheese whey supports high riboflavin synthesis by the engineered strains of the flavinogenic yeast Candida famata.

ABSTRACT:

Background

Riboflavin is a precursor of FMN and FAD which act as coenzymes of numerous enzymes. Riboflavin is an important biotechnological commodity with annual market sales exceeding nine billion US dollars. It is used primarily as a component of feed premixes, a food colorant, a component of multivitamin mixtures and medicines. Currently, industrial riboflavin production uses the bacterium, Bacillus subtilis, and the filamentous fungus, Ashbya gossypii, and utilizes glucose and/or oils as carbon substrates.

Results

We studied riboflavin biosynthesis in the flavinogenic yeast Candida famata that is a genetically stable riboflavin overproducer. Here it was found that the wild type C. famata is characterized by robust growth on lactose and cheese whey and the engineered stra

SUBMITTER: Ruchala J 

PROVIDER: S-EPMC9375410 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature